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Modafini/Modalert/Alertec - Modalert prescription
This Central Nervous System (CNS) stimulant is prescribed for narcolepsy, and prevents sufferers from falling asleep during the day.

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Modafini/Modalert/Alertec
Generic Name: Modafini/Modalert/Alertec (moe DA fih nill)
Brand Names: Provigil
What is the most important information I should know about Modafini/Modalert/Alertec?
• Use caution when driving, operating machinery, or performing other hazardous activities. Modafini/Modalert/Alertec may affect your judgment, thinking, or motor skills. If you experience any of these effects, avoid hazardous activities.
• It is best to avoid alcohol while taking Modafini/Modalert/Alertec. Alcohol or Modafini/Modalert/Alertec may have altered effects if taken together.
• Modafini/Modalert/Alertec may decrease the effects of hormonal methods of birth control including birth control pills and depot and implantable formulations (e.g., Norplant, Depo-Provera). Use a second, nonhormonal form of birth control while taking Modafini/Modalert/Alertec, and for one month after stopping Modafini/Modalert/Alertec, if prevention of pregnancy is desired.
• Modafini/Modalert/Alertec may be habit forming. You should discuss the abuse and dependence potential of Modafini/Modalert/Alertec with your doctor. Do not stop taking Modafini/Modalert/Alertec without first talking to your doctor. Your doctor may want to gradually lower the dose of the medication before stopping treatment.

What is Modafini/Modalert/Alertec?
• The exact way that Modafini/Modalert/Alertec works is not known.
• Modafini/Modalert/Alertec is used to improve wakefulness in patients with excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea/ hypoapnea syndrome (OSAHS), and shift work sleep disorder (SWSD).
• Modafini/Modalert/Alertec may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Modafini/Modalert/Alertec?
• Before taking Modafini/Modalert/Alertec, tell your doctor if you have
· left ventricular hypertrophy (enlarged left heart ventricle);
· chest pain, irregular heartbeats, or other symptoms of mitral valve prolapse due to central nervous system stimulant use;
· a recent history of a heart attack;
· high blood pressure;
· angina (chest pain);
· abused medicines called stimulants or street drugs;
· a history of mental illness;
· kidney disease; or
· liver disease.
• You may not be able to take Modafini/Modalert/Alertec, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Modafini/Modalert/Alertec is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take Modafini/Modalert/Alertec without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• It is not known whether Modafini/Modalert/Alertec passes into breast milk. Do not take Modafini/Modalert/Alertec without first talking to your doctor if you are breast-feeding.
• If you are older than 65 years of age, you may be more likely to experience side effects from Modafini/Modalert/Alertec. You may require a lower dose or special monitoring during treatment.

How should I take Modafini/Modalert/Alertec?
• Take Modafini/Modalert/Alertec exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Modafini/Modalert/Alertec can be taken with or without food.
• Modafini/Modalert/Alertec is usually taken once a day. Follow your doctor's instructions.
• It is important to take Modafini/Modalert/Alertec regularly to get the most benefit.
• Modafini/Modalert/Alertec is not a replacement for sleep. Modafini/Modalert/Alertec may reduce the signs of sleepiness, but may not completely treat this problem. Some drowsiness may continue. Potentially hazardous activities such as driving or operating machinery should only be performed if the level of wakefulness achieved is sufficient to permit such activities.
• Other treatments such as CPAP (continuous positive airway pressure) use should be continued as directed by your doctor if you have obstructive sleep apnea/ hypoapnea syndrome (OSAHS) and are taking Modafini/Modalert/Alertec.
• Modafini/Modalert/Alertec may be habit forming. You should discuss the abuse and dependence potential of Modafini/Modalert/Alertec with your doctor. Do not stop taking Modafini/Modalert/Alertec without first talking to your doctor. Your doctor may want to gradually lower the dose of the medication before stopping treatment.
• Store Modafini/Modalert/Alertec at room temperature away from moisture and heat.

What happens if I miss a dose Alertec Free Rx?
• Take the missed dose as soon as you remember as directed by your doctor. A missed dose taken late in the waking day may cause insomnia. If you don't remember until it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected.
• Symptoms of a Modafini/Modalert/Alertec overdose may include excitation, agitation, insomnia, sleep disturbances, anxiety, irritability, aggressiveness, confusion, nervousness, tremor, palpitations, nausea, and diarrhea.

What should I avoid while taking Modafini/Modalert/Alertec?
• Use caution when driving, operating machinery, or performing other hazardous activities. Modafini/Modalert/Alertec may affect your judgment, thinking, or motor skills. If you experience any of these effects, avoid hazardous activities.
• It is best to avoid alcohol while taking Modafini/Modalert/Alertec. Alcohol or Modafini/Modalert/Alertec may have altered effects if taken together.
• Modafini/Modalert/Alertec may decrease the effects of hormonal methods of birth control including birth control pills and depot and implantable formulations (e.g., Norplant, Depo-Provera). Use a second, nonhormonal form of birth control while taking Modafini/Modalert/Alertec, and for one month after stopping Modafini/Modalert/Alertec, if prevention of pregnancy is desired.

What are the possible side effects of Modafini/Modalert/Alertec?
• If you experience any of the following uncommon but serious side effects, stop taking Modafini/Modalert/Alertec and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
· irregular heartbeats;
· low or high blood pressure; or
· shortness of breath.
• Other, less serious side effects may be more likely to occur. Continue to take Modafini/Modalert/Alertec and talk to your doctor if you experience
· headache;
· infection;
· nausea, decreased appetite, or diarrhea;
· chills;
· dry mouth;
· runny nose;
· sore throat;
· nervousness;
· anxiety;
· dizziness;
· insomnia;
· depression; or
· numbness or tingling.
• Modafini/Modalert/Alertec may be habit forming. You should discuss the abuse and dependence potential of Modafini/Modalert/Alertec with your doctor. Do not stop taking Modafini/Modalert/Alertec without first talking to your doctor. Your doctor may want to gradually lower the dose of the medication before stopping treatment.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Modafini/Modalert/Alertec?
Modafini/Modalert/Alertec may decrease the effects of hormonal methods of birth control including birth control pills and depot and implantable formulations (e.g., Norplant, Depo-Provera). Use a second, nonhormonal form of birth control while taking Modafini/Modalert/Alertec, and for one month after stopping Modafini/Modalert/Alertec, if prevention of pregnancy is desired.
• Before taking Modafini/Modalert/Alertec, tell your doctor if you are taking any of the following drugs:
· a monoamine oxidase inhibitor (MAO inhibitor) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil);
· a tricyclic antidepressant such as clomipramine (Anafranil) or desipramine (Norpramin);
· another CNS stimulant such as amphetamine-dextroamphetamine (Adderall), methylphenidate (Ritalin, Methylin, Metadate ER, Concerta), pemoline (Cylert), and others;
· phenytoin (Dilantin);
· carbamazepine (Tegretol);
· phenobarbital;
· rifampin (Rifadin, Rimactane);
· ketoconazole (Nizoral);
· itraconazole (Sporanox);
· cyclosporine (Neoral, Sandimmune);
· theophylline (Theolair, Theochron, Theo-Bid, Theo-Dur, Elixophyllin, Slo-Phyllin, and others);
· warfarin (Coumadin);
· diazepam (Valium); or
· propranolol (Inderal).
• You may not be able to take Modafini/Modalert/Alertec, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact with Modafini/Modalert/Alertec. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

What is the most important information I should know about modalert/Modafini/Modalert/Alertec?

Use caution when driving, operating machinery, or performing otherhazardous activities. Modalert may affect your judgment, thinking, ormotor skills. If you experience any of these effects, avoid hazardousactivities. It is best to avoid alcohol while taking modalert. Alcoholor modalert may have altered effects if taken together.

Modalert may decrease the effects of hormonal methods of birthcontrol including birth control pills and depot and implantableformulations (e.g., Norplant, Depo-Provera). Use a second, nonhormonalform of birth control while taking modalert, and for one month afterstopping modalert, if prevention of pregnancy is desired.

Modalert may be habit forming. You should discuss the abuse anddependence potential of modalert with your doctor. Do not stop takingmodalert without first talking to your doctor. Your doctor may want togradually lower the dose of the medication before stopping treatment.

What is modalert?

The exact way that modalert works is not known.

Modalert is used to improve wakefulness in patients with excessivedaytime sleepiness associated with narcolepsy, obstructive sleepapnea/hypoapnea syndrome (OSAHS), and shift work sleep disorder (SWSD).

Modalert may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking modalert?

Before taking modalert, tell your doctor if you have

  • left ventricular hypertrophy (enlarged left heart ventricle);
  • chest pain, irregular heartbeats, or other symptoms of mitral valve prolapse due to central nervous system stimulant use;
  • a recent history of a heart attack;
  • high blood pressure;
  • angina (chest pain);
  • abused medicines called stimulants or street drugs;
  • a history of mental illness;
  • kidney disease; or
  • liver disease.You may not be able to take modalert, or you may require a dosageadjustment or special monitoring during treatment if you have any ofthe conditions listed above.

Modalert is in the FDA pregnancy category C. This means that it isnot known whether it will be harmful to an unborn baby. Do not takemodalert without first talking to your doctor if you are pregnant orcould become pregnant during treatment. It is not known whethermodalert passes into breast milk. Do not take modalert without firsttalking to your doctor if you are breast-feeding. If you are older than65 years of age, you may be more likely to experience side effects frommodalert. You may require a lower dose or special monitoring duringtreatment.How should I take modalert?

Take modalert exactly as directed by your doctor. If you do notunderstand these directions, ask your pharmacist, nurse, or doctor toexplain them to you.Take each dose with a full glass of water.

Modalert can be taken with or without food.

Modalert is usually taken once a day. Follow your doctor's instructions.

It is important to take modalert regularly to get the most benefit.

Modalert is not a replacement for sleep. Modalert may reduce thesigns of sleepiness, but may not completely treat this problem. Somedrowsiness may continue. Potentially hazardous activities such asdriving or operating machinery should only be performed if the level ofwakefulness achieved is sufficient to permit such activities.

Other treatments such as CPAP (continuous positive airway pressure)use should be continued as directed by your doctor if you haveobstructive sleep apnea/hypoapnea syndrome (OSAHS) and are takingmodalert.

Modalert may be habit forming. You should discuss the abuse anddependence potential of modalert with your doctor. Do not stop takingmodalert without first talking to your doctor. Your doctor may want togradually lower the dose of the medication before stopping treatment.Store modalert at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember as directed by yourdoctor. A missed dose taken late in the waking day may cause insomnia.If you don't remember until it is almost time for the next dose, skipthe missed dose and take only the next regularly scheduled dose. Do nottake a double dose of this medication unless otherwise directed by yourdoctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a modalert overdose may include excitation, agitation,insomnia, sleep disturbances, anxiety, irritability, aggressiveness,confusion, nervousness, tremor, palpitations, nausea, and diarrhea.

What should I avoid while taking modalert?

Use caution when driving, operating machinery, or performing otherhazardous activities. Modalert may affect your judgment, thinking, ormotor skills. If you experience any of these effects, avoid hazardousactivities. It is best to avoid alcohol while taking modalert. Alcoholor modalert may have altered effects if taken together.

Modalert may decrease the effects of hormonal methods of birthcontrol including birth control pills and depot and implantableformulations (e.g., Norplant, Depo-Provera). Use a second, nonhormonalform of birth control while taking modalert, and for one month afterstopping modalert, if prevention of pregnancy is desired.

What are the possible side effects of modalert?

If you experience any of the following uncommon but serious sideeffects, stop taking modalert and seek emergency medical attention orcontact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • irregular heartbeats;
  • low or high blood pressure; or
  • shortness of breath.

Other, less serious side effects may be more likely to occur.Continue to take modalert and talk to your doctor if you experience

  • headache;
  • infection;
  • nausea, decreased appetite, or diarrhea;
  • chills;
  • dry mouth;
  • runny nose;
  • sore throat;
  • nervousness;
  • anxiety;
  • dizziness;
  • insomnia;
  • depression; or
  • numbness or tingling.

Modalert may be habit forming. You should discuss the abuse anddependence potential of modalert with your doctor. Do not stop takingmodalert without first talking to your doctor. Your doctor may want togradually lower the dose of the medication before stopping treatment.

Side effects other than those listed here may also occur. Talk toyour doctor about any side effect that seems unusual or that isespecially bothersome.



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